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Anterior Ischemic Optic Neuropathy in Churg-Strauss Syndrome Neurol 44:2200-2202, Kattah,J.C.,et al, 1994 See this aricle in Pubmed Article Abstract A patient with a history of chronic rhinitis,sinusitis,and bronchial asthma developed a unilateral anterior ischemic optic neuropathy and a mild sensory motor neuropathy as the initial manifestation of systemic vasculitis.We made a probably diagnosis of Churg-Strauss syndrome. Fluorescein angiography showed delayed choroidal perfusion in both eyes. Marked eosinophilia,increased sedimentation rate,and elevated perinuclear anti-neutrophil cytoplasmic antibody and anti-myeloperoxidase antibody titers were the main laboratory abnormalities that supported this diagnosis.Therapy with high-dose methylprednisolone and cyclophosphamide may have preserved vision in the better seeing eye,improved its choroidal circulation,and reversed the laboratory abnormalities except for a mild persistent eosinophilia.The neuropathy is gradually improving.

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(click to filter results - removes previous filter) Churg-Strauss syndrome optic neuropathy optic neuropathy,ischemic optic neuropathy,ischemic,anterior

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